Background: The research and analysis from smoking must be from several points of view. Nevertheless the smoking economic burden by morbidity must be strongly researched since the Health Economy. The usefulness from postgraduate course about this subject offer the opportunity to generalize the whole knowledge obtained. Thus more health professional will be better capacitated to make better measures from the smoking economic impact over the Public Health. Objective: To design a postgraduate trainer course about the measurement from the smoking economic burden by morbidity. Materials and methods: Were used the inductive – deductive and the comparative as theoretical methods. As empiric method was used the bibliographic research. Results: The suggested course has the particularity of be contextualized agree to general learning needs from health professionals related to the smoking economic control. The course has the characteristic that each subject is supported by the previous. Conclusion: Was designed a postgraduate trainer course for health professionals related with the smoking economic control. The course is agreed to general learning needs from health professionals related to the smoking economic control.

Minks role in nature is important. Since mink is a carnivorous species, there are small mammals such as crayfish, snakes, turtles, small birds, mice, rabbits, insects, and crustaceans in the food chain. The most important of the practices that threaten the life of the mink is the cutting of the trees where the mink lives for furniture or energy production. Another threat is that their fur is made into clothes, as in Denmark, where 1 billion dollars of exports are made annually. However, the recent acceptance of the covid virus as a host to humans resulted in 17 million minks being buried in the mass grave in just the first week, and then the entire culling of them. Here it is not the resignation of a responsible prime minister. It is the threat that the mink, which forms part of the food chain, will suddenly increase the population of small birds, which play a key role in world food production. Of course, the purpose here is not to blame everyone unconsciously. However, instead of interfering with the chain in nature, the mink should be kept under quarantine by considering the antibody formed in the bodies of the mink as a treatment tool. Now the world should be prepared for unexpected adverse effects, such as the growing bird population with the disappearance of those 17 million minks. The species that need to be increased in the fight against Covid-19 are bats, the main source of the virus. Because bats may have carried a combination of SARS and MERS viruses from the same source in the past as a defense mechanism to adapt to nature with the depletion of water flies in the world with the restriction of water resources. The presence of any population in nature that is more than normal may further limit the use of a biosource present in nature. Every intervention in nature inevitably confronts humanity. As an alternative thought, it may be suggested that minks should not be considered as a commercial purpose in human life or should be restricted.

Endoscopic retrograde cholangiopancreatography (ERCP) in patients with surgical alterations in the normal biliary anatomy is technically challenging. We describe the case of a 73-year-old patient with an afferent limb syndrome secondary to a Whipple procedure for pancreatic cancer, in which a percutaneous rendezvous technique assisted in the endoscopic metallic stent placement with a favorable outcome.

Background: Honeybee’s venom is potent anticancer drug without exhibiting any side effects. Skin Basal Cell Carcinoma (SBCC) is a common malignancy. It can cause significant local destructions depending on affected site. The diagnosis of SBCC can be suspected from clinical findings and confirmation of diagnosis histopathology. The present SBCC is recurrent and aggressive in the skin of head [upper right, in front of the right ear]; the patient was 65 years old in time of first intervention. Materials & Methods: Following the lesions primarily surgically excised, the malignant growths recurrent and visual recognition occurred after 1 year from first operation, then another (the second) surgical removal of SBCC from affected skin with removal of all skin layers near the affected site but another recurrence visually occurs after about 4 months, in the form of malignant growth in the skin of right ear. Dry honeybee’s venom 1 mg was dissolved in 1 ml dist. water as injectable solution. Moreover, ointment contains 2% bee venom was prepared to be used topically inside affected ear as injection is not possible. Results: Before this novel intervention, the desperate patient situation seems very dangerous; as the new growths appear as continuous spread near the removed skin, so that patient’s family decided to apply more noninvasive and non-surgical intervention. The only precaution was testing the patients to assure she is not hypersensitive to honeybees’ venom. The treatment performed by subcutaneous injection of 0.3 ml from prepared Honeybees venom (0.1 % conc.) in the skin of affected part of the ear. Subcutaneous infiltration was applied around the lesions of about 0.5 ml as well, topical application of the ointment inside inner part of affected ear. This process repeated daily with cleaning of the ear every time by suitable safe and sterile saline solutions. Management of healing process was enhanced by ascorbic acid solution as topical application on dead cancer cells and to help in exudates debris removal. The complete removal of malignant growths and recovery obtained after 1 month from first bee venom injections. No recurrence of SBCC seen for 3 yrs. Conclusions: Honeybees venom is highly effective and safe anticancer drug that can be used for all patients’ categories of all ages. Regarding the present case invasive surgical intervention was not the good choice from the beginnings, as recurrence and giving chance for spreading following the time lapse between every surgery.